jennifer doudna h index

[22], In 2017, Doudna co-founded Mammoth Biosciences,[54] a San Francisco-based bioengineering tech startup. In 2015, Doudna was named by Time magazine as one of the 100 most influential people in the world. Jennifer Doudna and Emmanuelle Charpentier were awarded the Japan Prize today for their invention of the revolutionary gene-editing technology known as CRISPR-Cas9. The University of California has received two new patents for use of the revolutionary CRISPR-Cas9 technology, increasing its gene-editing patent portfolio to 10. To commercialize her CRISPR technologies, Doudna has founded several companies including Caribou Biosciences, Intellia Therapeutics, Mammoth Biosciences and Scribe Therapeutics. Two recent proof-of-concept studies using novel smartphone-based CRISPR technology coupled with optics and fluorescence detection may be poised to change how we approach not only rapid testing and screening, but also testing for acute infection. Jennifer A. Doudna, Ph.D., Professor of Molecular and Cell Biology and Chemistry at the University of California, Berkeley, has devoted her scientific career to revealing the secret life of RNA. [5] As of 2022[update], Doudna has an h-index of 141 according to Google Scholar[9] and of 111 according to Scopus. Bakar Labs, the facilitys flagship life sciences incubator, has been operational since mid-November, offering space to tenant companies. [14], In 2009, she took a leave of absence from Berkeley to work at Genentech to lead discovery research. April 21st, 2021, 2:45 PM PDT. Privacy| Accessibility | Nondiscrimination. UC Berkeley researchers have discovered how Cas1-Cas2, the proteins responsible for the ability of the CRISPR immune system in bacteria to adapt to new viral infections, identify the site in the genome where they insert viral DNA so they can recognize it later and mount an attack. [58] Mammoth Biosciences announced a peer-reviewed validation of a rapid, CRISPR-based point of need COVID-19 diagnostic which is faster and less expensive than qRT-PCR based tests. [61] Cate is a Berkeley professor and works on gene-editing yeast to increase their cellulose fermentation for biofuel production. [10][11] When Doudna was seven years old, the family moved to Hawaii so her father could accept a teaching position in American literature at the University of Hawaii at Hilo. Wed. 1 Mar 2023. UCSF Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH). Retrieved March 9, 2016. [10][11] Growing up in Hilo, Hawaii, Doudna was fascinated by the environmental beauty of the island and its flora and fauna. In an interview about the CRISPR gene-editing technology she co-invented, The US Patent and Trademark Office has granted UC its 20th US patent on CRISPR-Cas9 gene-editing technologies, co-invented by, In a series called "Women Shaping the Future,", The U.S. Patent and Trademark Office has decided to grant the, What Makes Omicron More Infectious Than Other COVID-19 Variants. Today, the U.S. Patent and Trademark Office granted a new CRISPR-Cas9 patent to the University of California, University of Vienna and Emmanuelle Charpentier covering new methods of gene editing in prokaryotic cells. See also:https://innovativegenomics.org, Taiwans top science award, theTang Prize, has gone to two UC Berkeley scientists well-known in the fields of biochemistry and physics: Jennifer Doudna, for her invention of CRISPR-Cas9 gene editing, and Arthur Rosenfeld, often called the godfather of energy efficiency.. The University of California, the University of Vienna and Emmanuelle Charpentier received an 11th U.S. patent involving CRISPR-Cas9, further expanding the reach of UCs patented technology relating to this revolutionary gene-editing tool. CRISPR-Cas9 opens up novel and wide-ranging possibilities across medicine, biology and agriculture. Her postdoctoral research was completed at Harvard Medical School, Massachusetts General Hospital and the University of Colorado. The team has now combined two different types of CRISPR enzymes to create an assay that can detect small amounts of viral RNA in less than an hour. Szostak. The remarkable breadth and depth of resources available to our students readies them as chemists and chemical engineers to address societys most urgent 21st-century issues. Doudna was awarded the 2020 Nobel Prize in Chemistry, along with Charpentier, for the development of a method for genome editing, CRISPR-Cas9. --"Royal Society Terms, conditions and policies". Two UC Berkeley scientists, Jennifer Doudna and John Ngai, each will receive a $100,000 Grand Challenges Explorations grant from the Bill & Melinda Gates Foundation to explore innovative research that could impact global health. Scientists from the Innovative Genomics Institute (IGI), the same UC Berkeley group that rapidly popped up a state-of-the-art COVID-19 testing laboratory in March, are now trialing a quicker way to obtain patient samples: through saliva. 11250. . The scientists developing the CRISPR test are from UCSF and Mammoth Biosciences, a startup co-founded and advised by. Doudna and Charpentier described how an RNA molecule guides the CRISPR-Cas9 system, binding it to a specific region in the DNA, and showed how the Cas9 protein then cuts the DNA, allowing it to be edited in a precise manner. Dr. Jennifer A. Doudna is the Li Ka Shing Chancellor's Chair and a Professor in the Departments of Chemistry and of Molecular and Cell Biology at the University of California, Berkeley. The book debuted at number one on The New York . As the Omicron variant of SARS-CoV-2 spread rapidly around the globe earlier this year, researchers at Gladstone Institutes, UC Berkeley, and the Innovative Genomics Institute used virus-like particles to identify which parts of the virus are responsible for its increased infectivity and spread. Jennifer A. Doudna, Ph.D Yale Medicine Magazine, 1999 - Spring Jennifer A. Doudna, Ph.D., professor of molecular biophysics and biochemistry and assistant investigator at the Howard Hughes Medical Institute, was one of 17 researchers honored by the National Academy of Sciences. Dr. BERKELEY, Calif. As a child in Hilo, one of the less touristy parts of Hawaii, Jennifer A. Doudna felt out of place. Her co-discovery of CRISPR-Cas9 genetic engineering technology, with collaborator, French scientist Emmanuelle Charpentier, has changed human and agricultural genomics research forever. Senior Investigator, Gladstone Institutes, Investigator, Howard Hughes Medical Institute, Professor, Molecular and Cell Biology and Chemistry, UC Berkeley, Li Ka Shing Chancellors Chair in Biomedical and Health Sciences, UC Berkeley, Faculty Scientist, Physical Biosciences Division, Lawrence Berkeley National Laboratory. The three most popular articles and their links. [44] Meanwhile, UC Berkeley and co-applicants' patent to cover the general technique was also granted. [7] She earned her Bachelor of Arts degree in Biochemistry in 1985. 1650 Owens Street, San Francisco, CA 94158, Embark: Presidential Postdoctoral Program, Gladstone Institute of Data Science and Biotechnology, Assay Development and Drug Discovery Core, Viral and Infectious Disease Research Program. leserforum wiener zeitung online. Check out College of Chemistry news articles and featured videos, as well as our biannual college magazine, Catalyst. Jennifer Doudna had recently arrived at Berkeley to accept a professorship in biochemistry when a colleague drew her attention to unusual bacteria found in an abandoned mine. The medal is awarded to distinguished individuals who have made valuable contributions in the fight against cancer through basic research, clinical research and cancer control. The University of California announced today that the U.S. Patent and Trademark Office has granted U.S. Patent Number10,113,167, covering unique RNA guides that, when combined with the Cas9 protein, are effective at homing in on and editing genes. She is the president of the Innovative Genomics Institute. Structural biologist and biochemist Jennifer Doudna has been honored with the 2019 Welfare Betterment Prize, a relatively new Hong Kong-based prize, for her pioneering discovery of CRISPR-Cas9 gene editing. Jennifer Doudna, a Nobel laureate in chemistry, was once described as "a salmon who swam upstream against the flow of male chauvinism ." Told about the description during an interview with . [81], She along with Charpentier was named one of the Time 100 most influential people in 2015,[19] and she was a runner-up for Time Person of the Year in 2016 alongside other CRISPR researchers.[34]. Jennifer Doudna is a senior investigator at Gladstone Institutes. Developing and applying novel CRISPR-based tools toward applications in biotechnology, diagnostics, neurodegenerative diseases, and other diseases. ", "Jennifer Doudna (UC Berkeley / HHMI): Genome Engineering with CRISPR-Cas9", "Into the Future with CRISPR Technology with Jennifer Doudna", CRISPR Scientist's Biography Explores Ethics Of Rewriting The Code Of Life, History of the creation-evolution controversy, Relationship between religion and science, Timeline of biology and organic chemistry, The Event Horizon Telescope Collaboration, European Organization for Nuclear Research CERN, Bangladesh Environmental Lawyers Association, Dejusticia: The Center for Law, Justice and Society, https://en.wikipedia.org/w/index.php?title=Jennifer_Doudna&oldid=1141324945, Fellows of the American Academy of Microbiology, Members of the National Academy of Medicine, Members of the Pontifical Academy of Sciences, Members of the United States National Academy of Sciences, University of California, Berkeley College of Letters and Science faculty, University of California, San Francisco faculty, Yale Department of Molecular Biophysics & Biochemistry faculty, Pages containing links to subscription-only content, Short description is different from Wikidata, All Wikipedia articles written in American English, Pages using Template:Post-nominals with customized linking, Articles containing potentially dated statements from 2022, All articles containing potentially dated statements, Nobelprize template using Wikidata property P8024, Interlanguage link template existing link, Creative Commons Attribution-ShareAlike License 3.0, First X-ray based structure of catalytic RNA, This page was last edited on 24 February 2023, at 13:51. On the morning that University of California, Berkeley, professor Jennifer Doudna won the 2020 Nobel Prize in Chemistry, her first stop after a 7 a.m. press conference and subsequent media interviews was her campus lab in the Innovative Genomics Institute. To date, CRISPR enzymes have been used to edit the genomes of one type of cell at a time: They cut, delete or add genes to a specific kind of cell within a tissue or organ, for example, or to one kind of microbe growing in a test tube. In thisOn My Mind feature, she describes how she first met Berkeleys newest Nobel laureate, Jennifer Doudna,who gave thanks to Banfield at Wednesdays press conference. Jennifer Doudna has been elected a member of the Institute of Medicine, considered one of the highest honors in the fields of medicine and health. [57] This center processes more than 1,000 patient samples per day. Please note: The views and opinions expressed in these articles are those of the authors and do not necessarily reflect the official policy or positions of UC Berkeley. [14] Doudna joined Yale's Department of Molecular Biophysics and Biochemistry as an assistant professor in 1994. She founded the Innovative Genomics Institute in 2014. The new Bakar Fellows Program is designed to help early-career Berkeley faculty commercialize promising research discoveries. Professor of Molecular and Cell Biology and Chemistry, UC Berkeley. Subscribe to our newsletter, Cell Signals, to receive monthly updates on the innovative discoveries, distinguishing awards, and noteworthy events taking place at Gladstone Institutes. Jennifer Doudna, professor of molecular and cell biology, is the 2014 recipient of the Lurie Prize in the Biomedical Sciences from the Foundation for the National Institutes of Health. An unprecedented collaboration between the Bay Areas three premier research universities. [14] She has been a co-recipient of the Gruber Prize in Genetics (2015),[15] the Tang Prize (2016),[16] the Canada Gairdner International Award (2016),[17] and the Japan Prize (2017). Simon & Schuster, $35. [2][20] Her father received his Ph.D. in English literature from the University of Michigan, and her mother, a stay-at-home parent, held a master's degree in education. [80] In 2021, Pope Francis appointed Doudna, and two other female Nobel laureates Donna Strickland and Emmanuelle Charpentier, as members of the Pontifical Academy of Sciences. Cotton Medal, The Texas A&M Section of the American Chemical Society, 2017 The Japan Prize, Japan Prize Foundation, 2017 Luminary Award, Precision Medicine World Conference, 2017 Fellow, American Association for Cancer Research, 2016 Honorary Doctorate of Science, Yale University, 2016 Honorary Doctorate of Science, York University, 2016 Tang Prize in Biopharmaceutical Science, Taiwan, 2016 Paul Allen Distinguished Investigator, 2016 Warren Alpert Foundation Prize, Harvard Medical School, 2016 Nakasone Award, Human Frontier Science Program, 2016 Paul Ehrlich and Ludwig Darmstaedter Prize, Germany, 2016 LOreal-UNESCO International Prize for Women in Science, 2015 Honorary Doctorate of Science, University of Leuven, 2015 Association of Biomolecular Resource Facilities Award, 2015 Charles Butcher Award, University of Colorado, 2015 Princess of Asturias Award for Technical and Scientific Research, 2015 International Society for Transgenic Technologies Prize, 2015 Time 100, Time Magazines 100 most influential people in the world, 2015 Fellow, American Society for Microbiology, 2014 Member, National Academy of Inventors, 2014 Foreign Policys 100 Leading Global Thinkers, 2014 Jacob Heskel Gabbay Award in Biotechnology and Medicine, 2014 Dr. Paul Janssen Award for Biomedical Research, 2010 Member, National Academy of Medicine, 2008 Fellow, American Association for the Advancement of Science, 2007 The Nucleic Acid Group Award, NACON VII, Sheffield, UK, 2003 Member, American Academy of Arts and Sciences, 2002 Member, National Academy of Sciences, 2000 Eli Lilly Award in Biological Chemistry, American Chemical Society, 2000 Jean Francois LeFevre Memorial Lectureship, CNRS, Strasbourg, France, 2000 R.B. [7] Her group has crystallized other ribozymes,[14] including the Hepatitis Delta Virus ribozyme. [60] As a postdoctoral researcher at the University of Colorado, Doudna met Jamie Cate, then a graduate student. The U.S. Patent and Trademark Office has issued a notice of allowance for a University of California patent application covering systems and methods for using single molecule guide RNAs that, when combined with the Cas9 protein, create more efficient and effective ways for scientists to target and edit genes. Note: On Oct. 7, 2020, Jennifer Doudna and her research collaborator Emmanuelle Charpentier were awarded the Nobel Prize in Chemistry for discovering the CRISPR gene-editing technology."This year's prize is about rewriting the code of life," said Goran Hansson, secretary-general of the Royal Swedish Academy of Sciences, as he announced the winners. The U.S. Patent and Trademark Office (USPTO) today granted the University of California (UC) and its partners, the University of Vienna and Emmanuelle Charpentier, a new CRISPR-Cas9 patent, bringing the teams continually expanding patent portfolio to 15. K chhai 2020-ngin tet-to Nobel Fa-hok Ching . [5], In 2002, she joined her husband, Jamie Cate, at Berkeley, accepting a position as professor of biochemistry and molecular biology. In 10 years, CRISPR transformed medicine. Today (Wednesday, Oct. 7), biochemist Jennifer Doudna won the 2020 Nobel Prize in Chemistry, with her colleague Emmanuelle Charpentier, for the co-development of CRISPR-Cas9, a revolutionary gene-editing tool that allows scientists to rewrite DNA. May 11, 2015. Transcript Tasked with a mission to manage Alfred Nobel's fortune and hasultimate responsibility for fulfilling the intentions of Nobel's will. "[3][4] She is the Li Ka Shing Chancellor's Chair Professor in the Department of Chemistry and the Department of Molecular and Cell Biology at the University of California, Berkeley. 2020 Jun;19(6):380-381. doi: 10.1038/d41573-020-00095-z. [5] From 1991 to 1994, she was Lucille P. Markey Postdoctoral Scholar in Biomedical Science at the University of Colorado Boulder, where she worked with Thomas Cech. The life processes of organisms are controlled by genes made up of sections of DNA. [5], At Yale, Doudna's group was able to crystallize and solve the three-dimensional structure of the catalytic core of the Tetrahymena Group I ribozyme. Jennifer Doudna, in full Jennifer Anne Doudna, (born February 19, 1964, Washington, D.C.), American biochemist best known for her discovery, with French microbiologist Emmanuelle Charpentier, of a molecular tool known as clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9. [65] She has also been a co-recipient of the Gruber Prize in Genetics (2015),[66] the Tang Prize (2016),[16] the Japan Prize (2017) and the Albany Medical Center Prize (2017). Jennifer Doudna and her colleagues showed that CRISPR/Cas9, can be used with great precision to selectively disable or add several genes at once in human cells, offering a potent new tool to understand and treat complex genetic diseases. [42] UC Berkeley appealed on grounds that they had clearly discussed and spelled out how to do the application the Broad had pursued. [47] In September 2013, Doudna cofounded Editas Medicine with Zhang and others despite their legal battles, but she quit in June 2014; Charpentier then invited her to join CRISPR Therapeutics, but she declined following the "divorce"-like experience at Editas. Title. All rights reserved. The new patent covers methods of targeting and binding or methods of cleaving a target DNA in a prokaryotic cell using Cas9 protein and single molecule DNA targeting RNAs. A simple, precise and inexpensive method for cutting DNA to insert genes into human cells could transform genetic medicine, making routine what now are expensive, complicated and rare procedures for replacing defective genes in order to fix genetic disease or even cure AIDS. Sort by citations Sort by year Sort by title. Doudna was born in Washington, D.C., and during her childhood, her family moved to Michigan and then to Hawaii. The College of Chemistry is consistently ranked as one of the best places on earth to learn, teach, and create new tools in the chemical sciences. Her lab's research into RNA biology led to the discovery of CRISPR-Cas9 as a tool for making targeted changes to the genome. 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